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Gematria Test Lab

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Gematria Test Lab is a service provider for the Household, Industrial, and Institutional Cleaners industry. It specializes in free radical research. Gematria offers a range of services including Antioxidant Power, Antiradical Potential Method, Coating Rate, RHF Radical Protection Factor, RSF Radical Sun/Skin Protection Factor, SAP Skin Antioxidative Protection, and Stability of Carrier Systems testing.
AP - Antioxidative Power GEMATRIA TEST LAB The determination of the Antioxidative Power (AP) of cosmetic formulations, raw materials allows to determine both the capacity and velocity of antioxidants to eliminate free radicals and to break radical chain reactions.
ARP - Antiradical Potential Method GEMATRIA TEST LAB The ARP method allows the quantification of the radical scavenging properties of topical applied formulations directly in skin.
CORA - Coating Rate GEMATRIA TEST LAB CORA is a comparative method which compares the photocatalytic activity of the photo catalyst alone in comparison with the activity of the coated photo catalyst.
RHF - Radical Hair Protection Factor GEMATRIA TEST LAB The RHF represents the ratio between the number Nu of generated radicals in the unprotected hair related to the number of generated radicals Np in the protected hair assuming the same applied UV dose for both.
RSF /Radical Sun / Skin Protection Factor GEMATRIA TEST LAB The RSF corresponds to the ratio between the number Nu of generated radicals in the unprotected skin related to the number Np of free radicals in the protected skin assuming a constant applied UV dose.
SAP (Skin Antioxidative Protection) GEMATRIA TEST LAB The SAP method allows the determination of the efficacy of a cosmetic or pharmaceutical antioxidant formulation inside the skin.
Stability of Carrier Systems GEMATRIA TEST LAB Determine the long term stability of nanoparticles in viscous and opaque medium and help to find the optimal formulation for each carrier system.
Penetration of Reactive Substances in the Skin Characterized by its Radical Status Factor (RSF) GEMATRIA TEST LAB The effect of external treatments of the skin, as the topical application of substances (cosmetics-UV filter, antioxidants), the protection by textiles or the application of aggressive detergents influence the free radical status of the skin and can be ch...view more The effect of external treatments of the skin, as the topical application of substances (cosmetics-UV filter, antioxidants), the protection by textiles or the application of aggressive detergents influence the free radical status of the skin and can be characterized by the Radical Skin/ Status Factor RSF. This factor demonstrates the relation between the Radica l Status (RS) of the untreated (RS untr) and treated skin (RS tr) : RSF = RS tr/RS untr. Substances or influences with a radical reducing effect results in a RSF > 1, with a radical increasing effect in a RSF < 1. No influence means accordingly RSF = 1. Therefore the RSF describes not only the UV- and Radical - protection of sunscreens but it is an universal factor for characterizing the whole radical status as a function of various exogenous and endogenous influences. view less
The Influence of the Cosmetic Formulation on the Radical Status of Skin GEMATRIA TEST LAB All skin treatments that influence the hydration degree of the skin and/or its barrier function may have a measurable influence on the radical generation. The highest effect was measured, when a solution of glycerine and water (50:50, w/w) was applied on ...view more All skin treatments that influence the hydration degree of the skin and/or its barrier function may have a measurable influence on the radical generation. The highest effect was measured, when a solution of glycerine and water (50:50, w/w) was applied on the skin. The amount of free radicals compared to untreated skin was nearly doubled. Thus, there are no placebos, from a dermatological viewpoint. Beyond the extinction characteristics of UV filters, their distribution inside a cosmetic formulation as well as their distribution pattern on the skin’s surface are the most important parameters that drive the efficacy of sunscreens. The more homogeneous is the film of UV filters on the skin, the higher will be the protective effect. The three model formulations, each exemplary for common sunscreen sprays, lotions, and creams, have very different performance on the skin. view less
The Multifactorial Influences on the Radical Status of Skin GEMATRIA TEST LAB Since radical reactions in biological systems are among the most important factors that lead to premature skin ageing and severe pathologies, many strategies have been attempt to prevent free radical damage. Free radical reactions are ubiquitous in biolog...view more Since radical reactions in biological systems are among the most important factors that lead to premature skin ageing and severe pathologies, many strategies have been attempt to prevent free radical damage. Free radical reactions are ubiquitous in biological systems and the multiple defence systems in all living organisms surely testify the evolutionary importance of these reactions. view less
The Radical Skin Factor (RSF) Distinguishes Between Cosmetic Formulations Acting as Radical Protector or Booster GEMATRIA TEST LAB The free radical status of the skin can be detected by spin probe assisted ESR spectroscopy which enables the quantification of radical processes in the skin. These measurements are the basis for the evaluation of cosmetical and pharmacological skin care ...view more The free radical status of the skin can be detected by spin probe assisted ESR spectroscopy which enables the quantification of radical processes in the skin. These measurements are the basis for the evaluation of cosmetical and pharmacological skin care products, as antioxidant creams as well as surface active agents with a radical boosting effect like detergents/surfactants or selftanners up to further external and internal applied substances influencing the radical process in skin. view less
The Role of Melanin as Protector Against Free Radicals in Skin and its Role as Free Radical Indicator in Hair GEMATRIA TEST LAB Throughout the body, melanin is a homogenous biological polymer containing a population of intrinsic, semiquinone-like radicals. Additional extrinsic free radicals are reversibly photo-generated by UV and visible light. Melanin photochemistry, particularl...view more Throughout the body, melanin is a homogenous biological polymer containing a population of intrinsic, semiquinone-like radicals. Additional extrinsic free radicals are reversibly photo-generated by UV and visible light. Melanin photochemistry, particularly the formation and decay of extrinsic radicals, has been the subject of numerous electron spin resonance (ESR) spectroscopy studies. Several melanin monomers exist, and the predominant monomer in a melanin polymer depends on its location within an organism. In skin and hair, melanin differs in content of eumelanin or pheomelanin. Its bioradical character and its susceptibility to UV irradiation makes melanin an excellent indicator for UV-related processes in both skin and hair. view less