Topiramate is a white to off-white powder. It was originally used as an anticonvulsant to treat epilepsy and other disorders that disorder that causes seizures and developmental delay. It is FDA approved, and widely used to treat migraines due to the effect it has on the blood vessels in the brain. It is used as a preventative for atypical migraine sufferers. It widens the blood vessels in the brain which become restricted by increased serotonin levels.

It has been found to be increasingly effective for migraine sufferers with limited side effects. Psychiatrists have used topiramate to treat bipolar disorder and they sometimes use topiramate to augment psychotropics, or to counteract the weight gain associated with numerous antidepressants. Topiramate has been investigated for use as treatment for an array of issues and is also used in clinical trials to treat post traumatic stress disorder.


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