The Mechanism of Action and Efficacy Evaluation Methods for Preservatives 

This paper discussed and reviewed the mechanism of action and factors influencing the preservative system in cosmetics. Three major evaluation methods (USP method, CTFA method and Linear-regression analysis) of Microbial challenge test have been compared to test preservatives’ efficacy. It has been pointed out that the microbial challenge test is an important means to evaluate the efficacy of preservatives.



Sino Lion is a global supplier of specialty chemicals for the Personal Care and Cosmetics industry. Their product list includes skin lighteners and enhancers, anti-microbial agents, anti-aging agents, cooling and warming agents, sunscreens, emulsifying agents, surfactants, skin and hair conditioners, emollients, natural products and polymers. Applications include a variety of body, face, hair and skin care products.